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1

Biosynthesis of vitamin B2: Structure and mechanism of riboflavin synthase

Markus Fischer, Adelbert Bacher

Journal:

Archives of Biochemistry and Biophysics

Year:

2008

Language:

english

File:

PDF, 2.38 MB

english, 2008

2

Biosynthesis of Vitamin B2: A Unique Way to Assemble a Xylene Ring

Prof. Dr. Markus Fischer, Prof. Dr. Dr. Adelbert Bacher

Journal:

Year:

2011

Language:

english

File:

PDF, 1.54 MB

english, 2011

3

Synthesis and Characterization of Cytidine Derivatives that Inhibit the Kinase IspE of the Non-Mevalonate Pathway for Isoprenoid Biosynthesis

Christine M. Crane, Anna K. H. Hirsch, Magnus S. Alphey, Tanja Sgraja, Susan Lauw, Victoria Illarionova, Felix Rohdich, Wolfgang Eisenreich, William N. Hunter, Adelbert Bacher, François Diederich

Journal:

Year:

2008

Language:

english

File:

PDF, 635 KB

english, 2008

4

Synthesis and Antiplasmodial Activity of Highly Active Reverse Analogues of the Antimalarial Drug Candidate Fosmidomycin

Christoph T. Behrendt, Andrea Kunfermann, Dr. Victoria Illarionova, An Matheeussen, Dr. Tobias Gräwert, Prof. Michael Groll, Dr. Felix Rohdich, Prof. Adelbert Bacher, Dr. Wolfgang Eisenreich, Prof. Dr

Journal:

Year:

2010

Language:

english

File:

PDF, 232 KB

english, 2010

5

Biosynthesis of 2-C-methyl-D-erythritol in plants by rearrangement of the terpenoid precursor, 1-deoxy-D-xylulose 5-phosphate

Silvia Sagner, Wolfgang Eisenreich, Monika Fellermeier, Christoph Latzel, Adelbert Bacher, Meinhart H. Zenk

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 250 KB

english, 1998

6

The deoxyxylulose phosphate pathway of terpenoid biosynthesis in plants and microorganisms

Wolfgang Eisenreich, Matthias Schwarz, Alain Cartayrade, Duilio Arigoni, Meinhart H. Zenk, Adelbert Bacher

Journal:

Chemistry & Biology

Year:

1998

Language:

english

File:

PDF, 6.67 MB

english, 1998

7

Biosynthesis of vitamin B2 : An essential zinc ion at the catalytic site of GTP cyclohydrolase II

Johannes Kaiser, Nicholas Schramek, Sabine Eberhardt, Stefanie Püttmer, Michael Schuster, Adelbert Bacher

Journal:

Year:

2002

Language:

english

File:

PDF, 264 KB

english, 2002

8

Biosynthesis of vitamin B2 in plants

Markus Fischer, Adelbert Bacher

Journal:

Physiologia Plantarum

Year:

2006

Language:

english

File:

PDF, 1.35 MB

english, 2006

9

Light-induced reactions of Escherichia coli DNA photolyase monitored by Fourier transform infrared spectroscopy

Erik Schleicher, Benedikt Heßling, Viktoria Illarionova, Adelbert Bacher, Stefan Weber, Gerald Richter, Klaus Gerwert

Journal:

Year:

2005

Language:

english

File:

PDF, 288 KB

english, 2005

10

Evolution of Vitamin B2 Biosynthesis. A Novel Class of Riboflavin Synthase in Archaea

Markus Fischer, Anne-Kathrin Schott, Werner Römisch, Arne Ramsperger, Martin Augustin, Alexander Fidler, Adelbert Bacher, Gerald Richter, Robert Huber, Wolfgang Eisenreich

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 464 KB

english, 2004

11

Deoxyxylulose phosphate pathway to terpenoids

Wolfgang Eisenreich, Felix Rohdich, Adelbert Bacher

Journal:

Trends in Plant Science

Year:

2001

Language:

english

File:

PDF, 162 KB

english, 2001

12

Biosynthetic Origin of a Branched Chain Analogue of the Lipase Inhibitor, Lipstatin

Eisenreich, Wolfgang, Kupfer, Ernst, Stohler, Peter, Weber, Wolfgang, Bacher, Adelbert

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 141 KB

english, 2003

13

Terpenoid Biosynthesis from 1-Deoxy-D-Xylulose in Higher Plants by Intramolecular Skeletal Rearrangement

Duilio Arigoni, Silvia Sagner, Christoph Latzel, Wolfgang Eisenreich, Adelbert Bacher and Meinhart H. Zenk

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1007 KB

english, 1997

14

Dimethylallyl Pyrophosphate Is Not the Committed Precursor of Isopentenyl Pyrophosphate during Terpenoid Biosynthesis from 1-Deoxyxylulose in Higher Plants

Duilio Arigoni, Wolfgang Eisenreich, Christoph Latzel, Silvia Sagner, Tanja Radykewicz, Meinhart H. Zenk and Adelbert Bacher

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 863 KB

english, 1999

15

Stereochemical course of the reduction step in the formation of 2-C-methylerythritol from the terpene precursor 1-deoxyxylulose in higher plants

Arigoni, Duilio, Giner, José-Luis, Sagner, Silvia, Wungsintaweekul, Juraithip, Zenk, Meinhart H., Kis, Klaus, Bacher, Adelbert, Eisenreich, Wolfgang

Journal:

Chemical Communications

Year:

1999

Language:

english

File:

PDF, 86 KB

english, 1999

16

Evolution of vitamin B2 biosynthesis: riboflavin synthase of Arabidopsis thaliana and its inhibition by riboflavin

Fischer, Markus, Haase, Ilka, Feicht, Richard, Schramek, Nicholas, Köhler, Peter, Schieberle, Peter, Bacher, Adelbert

Journal:

Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 624 KB

english, 2005

17

Femtosecond to Millisecond Dynamics of Light Induced Allostery in the Avena sativa LOV Domain

Gil, Agnieszka A., Laptenok, Sergey P., French, Jarrod B., Iuliano, James N., Lukacs, Andras, Hall, Christopher R., Sazanovich, Igor V., Greetham, Gregory M., Bacher, Adelbert, Illarionov, Boris, Fisc

Journal:

Journal of Physical Chemistry B

Year:

2017

Language:

english

File:

PDF, 4.53 MB

english, 2017

18

Unexpected Biosynthetic Precursors of Amarogentin − A Retrobiosynthetic 13C NMR Study

Chang-Zeng Wang, Ulrich H. Maier, Wolfgang Eisenreich, Petra Adam, Ingrid Obersteiner, Michael Keil, Adelbert Bacher, Meinhart H. Zenk

Journal:

European Journal of Organic Chemistry

Year:

2001

Language:

english

File:

PDF, 385 KB

english, 2001

19

Studies on the Non-Mevalonate Pathway − Preparation and Properties of Isotope-Labeled 2C-Methyl-D-erythritol 2,4-Cyclodiphosphate

Christoph A. Schuhr, Stefan Hecht, Klaus Kis, Wolfgang Eisenreich, Juraithip Wungsintaweekul, Adelbert Bacher, Felix Rohdich

Journal:

European Journal of Organic Chemistry

Year:

2001

Language:

english

File:

PDF, 298 KB

english, 2001

20

Design of Biofunctional Assemblies on Solids through Recombinant Spherical Bacterial Protein Lumazine Synthase

Markus Fischer, Adelbert Bacher, Ilka Haase, Matthias Tristl, Erich Sackmann

Journal:

Year:

2001

Language:

english

File:

PDF, 208 KB

english, 2001

21

Synthesis of Nanophase Iron Oxide in Lumazine Synthase Capsids

Wayne Shenton, Stephen Mann, Helmut Cölfen, Adelbert Bacher, Markus Fischer

Journal:

Angewandte Chemie

Year:

2001

Language:

english

File:

PDF, 192 KB

english, 2001

22

Synthesis of Nanophase Iron Oxide in Lumazine Synthase Capsids

Wayne Shenton, Stephen Mann, Helmut Cölfen, Adelbert Bacher, Markus Fischer

Journal:

Angewandte Chemie International Edition

Year:

2001

Language:

english

File:

PDF, 196 KB

english, 2001

23

Fluoreszierende Inhibitoren von IspF, einem Enzym im “Nicht-Mevalonat-Biosyntheseweg” der Isoprenoide und möglichen Ziel einer Antimalariatherapie

Christine M. Crane, Johannes Kaiser, Nicola L. Ramsden, Susan Lauw, Felix Rohdich, Wolfgang Eisenreich, William N. Hunter, Adelbert Bacher, François Diederich

Journal:

Angewandte Chemie

Year:

2006

Language:

german

File:

PDF, 344 KB

german, 2006

24

IspH-Protein von Escherichia coli – Struktur und Mechanismus

Tobias Gräwert, Felix Rohdich, Ingrid Span, Adelbert Bacher, Wolfgang Eisenreich, Jörg Eppinger, Michael Groll

Journal:

Angewandte Chemie

Year:

2009

File:

PDF, 787 KB

2009

25

Reduktive Dehydroxylierung von Allylalkoholen durch IspH-Protein

Dr. Tobias Gräwert, Ingrid Span, Prof. Dr. Dr. Adelbert Bacher, Prof. Dr. Michael Groll

Journal:

Angewandte Chemie

Year:

2010

Language:

german

File:

PDF, 1.02 MB

german, 2010

26

Fluorescent Inhibitors for IspF, an Enzyme in the Non-Mevalonate Pathway for Isoprenoid Biosynthesis and a Potential Target for Antimalarial Therapy

Christine M. Crane, Johannes Kaiser, Nicola L. Ramsden, Susan Lauw, Felix Rohdich, Wolfgang Eisenreich, William N. Hunter, Adelbert Bacher, François Diederich

Journal:

Angewandte Chemie International Edition

Year:

2006

Language:

english

File:

PDF, 340 KB

english, 2006

27

Structure of Active IspH Enzyme from Escherichia coli Provides Mechanistic Insights into Substrate Reduction

Tobias Gräwert, Felix Rohdich, Ingrid Span, Adelbert Bacher, Wolfgang Eisenreich, Jörg Eppinger, Michael Groll

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 839 KB

english, 2009

28

Reductive Dehydroxylation of Allyl Alcohols by IspH Protein

Dr. Tobias Gräwert, Ingrid Span, Prof. Dr. Dr. Adelbert Bacher, Prof. Dr. Michael Groll

Journal:

Angewandte Chemie International Edition

Year:

2010

Language:

english

File:

PDF, 1.12 MB

english, 2010

29

Crystal Structure of Methylornithine Synthase (PylB): Insights into the Pyrrolysine Biosynthesis

Felix Quitterer, Anja List, Priv.-Doz. Dr. Wolfgang Eisenreich, Prof. Dr. Dr. Adelbert Bacher, Prof. Dr. Michael Groll

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 1.30 MB

english, 2012

30

Cover Picture: Crystal Structure of Methylornithine Synthase (PylB): Insights into the Pyrrolysine Biosynthesis (Angew. Chem. Int. Ed. 6/2012)

Felix Quitterer, Anja List, Priv.-Doz. Dr. Wolfgang Eisenreich, Prof. Dr. Dr. Adelbert Bacher, Prof. Dr. Michael Groll

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 983 KB

english, 2012

31

Stereochemical Studies on the Making and Unmaking of Isopentenyl Diphosphate in Different Biological Systems

Ralf Laupitz, Tobias Gräwert, Christoph Rieder, Ferdinand Zepeck, Adelbert Bacher, Duilio Arigoni, Felix Rohdich, Wolfgang Eisenreich

Journal:

Chemistry & Biodiversity

Year:

2004

Language:

english

File:

PDF, 227 KB

english, 2004

32

Stereochemical Studies on the Making and Unmaking of Isopentenyl Diphosphate in Different Biological Systems

Ralf Laupitz, Tobias Gräwert, Christoph Rieder, Ferdinand Zepeck, Adelbert Bacher, Duilio Arigoni, Felix Rohdich, Wolfgang Eisenreich

Journal:

Chemistry & Biodiversity

Year:

2004

File:

PDF, 29 KB

2004

33

ChemInform Abstract: Design and Synthesis of 6-(6-D-Ribitylamino-2,4-dihydroxypyrimidin-5-yl)-1-hexylphosphonic Acid, a Potent Inhibitor of Lumazine Synthase.

Mark Cushman, Jeffrey T. Mihalic, Klaus Kis, Adelbert Bacher

Journal:

Year:

1999

File:

PDF, 30 KB

1999

34

ChemInform Abstract: Investigation of the Binding of Fluorolumazines to the 1-MDa Capsid of Lumazine Synthase by 15N{19F} REDOR NMR.

Jon M. Goetz, Barbara Poliks, Daniel R. Studelska, Markus Fischer, Karl Kugelbrey, Adelbert Bacher, Mark Cushman, Jacob Schaefer

Journal:

Year:

1999

File:

PDF, 33 KB

1999

35

ChemInform Abstract: 19F NMR Ligand Perturbation Studies on 6,7-Bis(trifluoromethyl)-8-ribityllumazine-7-hydrates and the Lumazine Synthase Complex of Bacillus subtilis. Site-Directed Mutagenesis Changes the Mechanism and the Stereoselectivity of the Catalyzed Haloform-Type Reaction.

Johannes Scheuring, Karl Kugelbrey, Sevil Weinkauf, Mark Cushman, Adelbert Bacher, Markus Fischer

Journal:

Year:

2001

File:

PDF, 30 KB

2001

36

ChemInform Abstract: Unexpected Biosynthetic Precursors of Amarogentin — A Retrobiosynthetic 13C NMR Study.

Chang-Zeng Wang, Ulrich H. Maier, Wolfgang Eisenreich, Petra Adam, Ingrid Obersteiner, Michael Keil, Adelbert Bacher, Meinhart H. Zenk

Journal:

Year:

2002

File:

PDF, 29 KB

2002

37

Design, Synthesis, and Evaluation of Acyclic C-Nucleoside and N-Methylated Derivatives of the Ribitylaminopyrimidine Substrate of Lumazine Synthase as Potential Enzyme Inhibitors and Mechanistic Probes.

Jinhua Chen, Thota Sambaiah, Boris Illarionov, Markus Fischer, Adelbert Bacher, Mark Cushman

Journal:

Year:

2005

File:

PDF, 15 KB

2005

38

Biosynthesis of Flavocoenzymes

Markus Fischer, Adelbert Bacher

Journal:

Year:

2005

File:

PDF, 8 KB

2005

39

Design, Synthesis, and Biochemical Evaluation of 1,5,6,7-Tetrahydro-6,7-dioxo-9-D-Ribitylaminolumazines Bearing Alkyl Phosphate Substituents as Inhibitors of Lumazine Synthase and Riboflavin Synthase.

Mark Cushman, Guangyi Jin, Boris Illarionov, Markus Fischer, Rudolf Ladenstein, Adelbert Bacher

Journal:

Year:

2005

File:

PDF, 8 KB

2005

40

ChemInform Abstract: Reductive Dehydroxylation of Allyl Alcohols by IspH Protein

Tobias Graewert, Ingrid Span, Adelbert Bacher, Michael Groll

Journal:

Year:

2011

File:

PDF, 20 KB

2011

41

ChemInform Abstract: Biosynthesis of Vitamin B2: A Unique Way to Assemble a Xylene Ring

Markus Fischer, Adelbert Bacher

Journal:

Year:

2011

File:

PDF, 18 KB

2011

42

Nonphosphate Inhibitors of IspE Protein, a Kinase in the Non-Mevalonate Pathway for Isoprenoid Biosynthesis and a Potential Target for Antimalarial Therapy

Anna K. H. Hirsch, Susan Lauw, Philipp Gersbach, W. Bernd Schweizer, Felix Rohdich, Wolfgang Eisenreich, Adelbert Bacher, François Diederich

Journal:

Year:

2007

Language:

english

File:

PDF, 358 KB

english, 2007

43

Probing the N(5)H Bond of the Isoalloxazine Moiety of Flavin Radicals by X- and W-Band Pulsed Electron–Nuclear Double Resonance

Stefan Weber, Christopher W. M. Kay, Adelbert Bacher, Gerald Richter, Robert Bittl

Journal:

Year:

2005

Language:

english

File:

PDF, 147 KB

english, 2005

44

Determination of the Chemical Structure of Linden Ether

Imre Blank, Werner Grosch, Wolfgang Eisenreich, Adelbert Bacher, Joachim Firl

Journal:

Helvetica Chimica Acta

Year:

1990

Language:

english

File:

PDF, 382 KB

english, 1990

45

Structure-Based Design and Synthesis of the First Weak Non-Phosphate Inhibitors for IspF, an Enzyme in the Non-Mevalonate Pathway of Isoprenoid Biosynthesis

Corinne Baumgartner, Christian Eberle, François Diederich, Susan Lauw, Felix Rohdich, Wolfgang Eisenreich, Adelbert Bacher

Journal:

Helvetica Chimica Acta

Year:

2007

Language:

english

File:

PDF, 583 KB

english, 2007

46

Resonance Raman spectroscopic study of the neutral flavin radical complex of DNA photolyase from Escherichia coli

Daniel H. Murgida, Erik Schleicher, Adelbert Bacher, Gerald Richter, Peter Hildebrandt

Journal:

Journal of Raman Spectroscopy

Year:

2001

Language:

english

File:

PDF, 172 KB

english, 2001

47

Phosphates of riboflavin and riboflavin analogs: A reinvestigation by high-performance liquid chromatography

Peter Nielsen, Peter Rauschenbach, Adelbert Bacher

Journal:

Analytical Biochemistry

Year:

1983

Language:

english

File:

PDF, 743 KB

english, 1983

48

Perspectives in anti-infective drug design. The late steps in the biosynthesis of the universal terpenoid precursors, isopentenyl diphosphate and dimethylallyl diphosphate

Felix Rohdich, Adelbert Bacher, Wolfgang Eisenreich

Journal:

Bioorganic Chemistry

Year:

2004

Language:

english

File:

PDF, 1.36 MB

english, 2004

49

A high-throughput screening platform for inhibitors of the riboflavin biosynthesis pathway

Johannes Kaiser, Boris Illarionov, Felix Rohdich, Wolfgang Eisenreich, Sabine Saller, Jan Van den Brulle, Mark Cushman, Adelbert Bacher, Markus Fischer

Journal:

Analytical Biochemistry

Year:

2007

Language:

english

File:

PDF, 449 KB

english, 2007

50

Virtual screening, selection and development of a benzindolone structural scaffold for inhibition of lumazine synthase

Arindam Talukdar, Ekaterina Morgunova, Jianxin Duan, Winfried Meining, Nicolas Foloppe, Lennart Nilsson, Adelbert Bacher, Boris Illarionov, Markus Fischer, Rudolf Ladenstein, Mark Cushman

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 927 KB

english, 2010

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